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Results for "

anticholinergic agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Calcium Channel (1) Cholinesterase (ChE) (3) Dopamine Receptor (8) Dopamine Transporter (1) Drug Metabolite (1) Histamine Receptor (7) iGluR (1) Influenza Virus (1) Isotope-Labeled Compounds (4) mAChR (26) mGluR (1) NF-κB (2) Potassium Channel (4)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Endocrinology (1) Infection (1) Inflammation/Immunology (6) Metabolic Disease (2) Neurological Disease (34)

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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1607

Chlorphenoxamine 1 Publications Verification	Histamine Receptor	Neurological Disease Endocrinology
Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.

HY-117633

Sultroponium

Atropine sulfobetaine; A-118
Cholinesterase (ChE) Neurological Disease

Sultroponium (A118) is an anticholinergic agent .

Sultroponium Atropine sulfobetaine; A-118	Cholinesterase (ChE)	Neurological Disease
Sultroponium (A118) is an anticholinergic agent .

HY-116550

Piroheptine hydrochloride	Dopamine Transporter	Neurological Disease
Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson .

HY-U00001

Phenglutarimid

Ciba 10870; Phenglutarimide
mAChR Neurological Disease

Phenglutarimid is an anticholinergic used as an antiparkinsonian agent.
HY-W201842

Octamylamine

mAChR Neurological Disease

Octamylamine is an anticholinergic and antispasmodic agent .
HY-U00184

Timepidium bromide

Sesden; SA504
mAChR Cardiovascular Disease

Timepidium bromide (Sesden; SA504) is an anticholinergic agent.

Phenglutarimid Ciba 10870; Phenglutarimide	mAChR	Neurological Disease
Phenglutarimid is an anticholinergic used as an antiparkinsonian agent.

Octamylamine	mAChR	Neurological Disease
Octamylamine is an anticholinergic and antispasmodic agent .

Timepidium bromide Sesden; SA504	mAChR	Cardiovascular Disease
Timepidium bromide (Sesden; SA504) is an anticholinergic agent.

HY-118406

Ethybenztropine Ponalid; UK 738	mAChR	Neurological Disease
Ethybenztropine (Ponalid) is a muscarinic receptor blocker. Ethybenztropine is an anticholinergic and antihistaminergic agent .

HY-B1343

Pridinol mesylate

Cholinesterase (ChE) Neurological Disease

Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .
HY-B0547

Homatropine

mAChR Neurological Disease

Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .
HY-B0547A

Homatropine Bromide

mAChR Neurological Disease

Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .
HY-105771

Parapenzolate bromide

mAChR Neurological Disease

Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent .

Pridinol mesylate	Cholinesterase (ChE)	Neurological Disease
Pridinol mesylate is an orally active and potent central *anticholinergic* agent, and acts as muscle relaxant .

Homatropine	mAChR	Neurological Disease
Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .

Homatropine Bromide	mAChR	Neurological Disease
Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .

Parapenzolate bromide	mAChR	Neurological Disease
Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent .

HY-U00105

Oxitropium Bromide	mAChR	Inflammation/Immunology
Oxitropium bromide is an mAChR antagonist used as an anticholinergic bronchodilator agent for the treatment of asthma and chronic obstructive pulmonary disease.

HY-B1806A

Tridihexethyl chloride Pathilon chloride	mAChR	Neurological Disease Inflammation/Immunology
Tridihexethyl (Pathilon) chloride is an orally active *anticholinergic* agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus .

HY-105710

Tropatepine	Others	Neurological Disease
Tropatepine is an orally active, *anticholinergic* muscarinic antagonist and can be used as an antiparkinsonian agent . Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic agents .

HY-B2112

Valethamate bromide
Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilation .

HY-117284

Eucatropine	mAChR	Neurological Disease
Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC₅₀ value of 0.583 μM. Eucatropine is an anticholinergic agent .

HY-122520

Fentonium bromide	Others	Neurological Disease
Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions .

HY-118524A

Dipiproverine hydrochloride LD-935	Others	Neurological Disease
Dipiproverine (hydrochloride) is the hydrochloride form of Dipiproverine (HY-118524). Dipiproverine (hydrochloride) is an alpha-amino acid ester, an antispasmodic compound, which is used as an anticholinergic agent .

HY-N7061

Tropine	Others	Neurological Disease
Tropine is a secondary metabolite of Solanaceae plants, is an *anticholinergic* agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-W373206

Triampyzine	Others	Metabolic Disease
Triampizine is an effective gastric antisecretory agent. Triampizine does not have the side effects commonly associated with anticholinergic agents. Triampizine may react with the excipient magnesium stearate. Triampizine can be used in the research of hyperacidity .

HY-B1667

Isopropamide iodide
Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility .

HY-B0267AS

Oxybutynin-d11 chloride	Isotope-Labeled Compounds mAChR Potassium Channel	Neurological Disease
Oxybutynin-d₁₁ (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1].

HY-W354753

Homatropine hydrochloride	mAChR	Others
Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .

HY-U00055

Temiverine hydrochloride	mAChR	Neurological Disease
Temiverine hydrochloride is a synthesized agent that is expected to have anticholinergic action. Temiverine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1470

Azaperone R-1929	Dopamine Receptor	Neurological Disease
Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

HY-120081A

Metixene hydrochloride hydrate 1 Publications Verification	Others	Neurological Disease
Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hydrate potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC₅₀ and K_i values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used for the research of parkinsonian .

HY-120081B

Metixene hydrochloride	Others	Neurological Disease
Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC₅₀ and K_i values of 55 nM and 15 nM, respectively. Metixene hydrochloride can be used for the research of parkinsonian .

HY-135407S

N-Desethyl Oxybutynin-d5 hydrochloride	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
N-Desethyl Oxybutynin-d₅ (hydrochloride) is deuterium labeled N-Desethyl Oxybutynin hydrochloride. N-Desethyl Oxybutynin is the the active metabolite Oxybutynin. Oxybutynin is an anticholinergic agent that inhibits voltage-dependent K+ channels[1].

HY-B1483

Methapyrilene hydrochloride Thenylpyramine hydrochloride
Methapyrilene (Thenylpyramine) hydrochloride is an orally active H1-receptor antihistamine and an anticholinergic agent of the pyridine chemical class. Methapyrilene hydrochloride has hepatotoxicity and can be used as a hepatotoxin that cause periportal hepatic necrosis in vivo

HY-145391

Triperiden	Influenza Virus	Infection
Triperiden is an inhibitor of influenza virus multiplication. Triperiden targets the haemagglutinin of fowl plague virus (FPV) for antiviral activity and acts by inhibiting the conformational change in the haemagglutinin at acid pH. Triperiden is also anticholinergic anti-parkinsonism agent .

HY-120081

Metixene	Others	Neurological Disease
Metixene (Piperidine) is an anticholinergic and antiparkinsonian agent. Metixene potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC₅₀ and K_i values of 55 nM and 15 nM, respectively. Metixene can be used for the research of parkinsonian .

HY-B0520A

Benztropine mesylate 4 Publications Verification Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate	Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B1487

Procyclidine hydrochloride Tricyclamol hydrochloride; (±)-Procyclidine hydrochloride	iGluR mAChR	Neurological Disease
Procyclidine (Tricyclamol, (±)-Procyclidine) hydrochloride , an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine hydrochloride can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy .

HY-B1487A

Procyclidine Tricyclamol; (±)-Procyclidine
Procyclidine (Tricyclamol; (±)-Procyclidine), an anticholinergic agent, is a muscarinic receptor antagonist that also has the properties of an N-methyl-D-aspartate (NMDA) antagonist. Procyclidine can be used in studies of Parkinson's disease and related psychiatric disorders such as Soman-induced epilepsy .

HY-16489

Terodiline	Potassium Channel mAChR Calcium Channel	Metabolic Disease
Terodiline, an antispasmodic agent, blocks hERG current with the IC₅₀ of 375 nM. Terodiline has both *anticholinergic* and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability. Terodiline can be used for the research of urinary incontinence .

HY-B0520

Benztropine Benzatropine; Benzotropine	Dopamine Receptor mAChR Histamine Receptor
Benztropine (Benzatropine; Benzotropine) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research . Benztropine is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B1470S

Azaperone-d4 R-1929-d₄	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease
Azaperone-d₄ is the deuterium labeled Azaperone. Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

HY-B0761

(R,R)-Glycopyrrolate (R,R)-Glycopyrronium bromide; (R,R)-Glycopyrrolate bromide	mAChR	Neurological Disease
(R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) is an *anticholinergic* agent. (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) has the ability to reduce the frequency of drooling in vivo with developmental disabilities .

HY-14263

Pericyazine Propericiazine; RP 8909	Dopamine Receptor	Neurological Disease
Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis . Pericyazine is a selective D2-dopamine receptor antagonist . Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects .

HY-B0267

Oxybutynin	mAChR Potassium Channel	Neurological Disease
Oxybutynin is an anticholinergic agent, which inhibits vascular K_v channels in a concentration-dependent manner, with an IC₅₀ of 11.51 μM . Oxybutynin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-137976

Penehyclidine hydrochloride Penequinine hydrochloride	mAChR NF-κB	Inflammation/Immunology
Penehyclidine (Penequinine) hydrochloride, a *anticholinergic* agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine hydrochloride activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine hydrochloride can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation .

HY-142119

Penehyclidine	mAChR NF-κB	Inflammation/Immunology
Penehyclidine, a *anticholinergic* agent, is a selective antagonist of M1 and M3 receptors. Penehyclidine activates NF-kβ in lung tissue and inhibits the release of inflammatory factors. Penehyclidine can alleviate the pulmonary inflammatory response in rats with chronic obstructive pulmonary disease (COPD) undergoing mechanical ventilation .

HY-B0520AR

Benztropine mesylate (Standard) Benzatropine mesylate (Standard); Benzotropine mesylate (Standard); Benztropine methanesulfonate (Standard)	Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine (mesylate) (Standard) is the analytical standard of Benztropine (mesylate). This product is intended for research and analytical applications. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-B0520AS1

Benztropine-d3 mesylate	Dopamine Receptor Histamine Receptor mAChR
Benztropine-d₃ (mesylate) is the deuterium labeled Benztropine mesylate[1]. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[2][3].

HY-109013

Sofpironium bromide BBI 4000	mAChR	Neurological Disease
Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes .

HY-B0520AS

Benztropine-13C,d3 mesylate	Isotope-Labeled Compounds Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine- ¹³C,d₃ (mesylate) is the ¹³C- and deuterium labeled Benztropine (mesylate). Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[1][2].

HY-155822

TZ3O	Cholinesterase (ChE)	Neurological Disease
TZ3O (compound TZ30) is an anticholinergic agent with neuroprotective effects. TZ3O (2 mg/kg, 4 mg/kg) can improve memory impairment and cognitive decline in rats in the Scopolamine (HY-N0296)-induced Alzheimer-type model. TZ3O could be used in Alzheimer’s research .

HY-105793

Mazaticol	mAChR	Neurological Disease
Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research .

HY-106577

Cibenzoline Cifenline; Ro 22-7796	Potassium Channel	Cardiovascular Disease
Cibenzoline is a potent inhibitor of KATP channel with directly affecting the pore-forming Kir6.2 subunit rather than the SUR1 subunit. Cibenzoline is a class Ia antiarrhythmic agent. Cibenzoline has little anticholinergic activity. Cibenzoline markedly attenuate LVPG which has a close relationship with myocardial contractility decreasing. Cibenzoline has the potential for the research of hypertrophic obstructive cardiomyopathy .

HY-136587

Oxomemazine	Histamine Receptor mGluR	Inflammation/Immunology
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (K_i= 84 nM, M1 receptor) and low (K_i= 1.65 μM, M2 receptor) affinity sites . Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7061

Tropine	Alkaloids Structural Classification Microorganisms Other Alkaloids Source classification Plants Solanaceae Przewalskia tangutica Maximo.	Others
Tropine is a secondary metabolite of Solanaceae plants, is an *anticholinergic* agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

Cat. No.	Product Name	Chemical Structure

HY-B0267AS

Oxybutynin-d11 chloride
Oxybutynin-d₁₁ (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1].

HY-135407S

N-Desethyl Oxybutynin-d5 hydrochloride
N-Desethyl Oxybutynin-d₅ (hydrochloride) is deuterium labeled N-Desethyl Oxybutynin hydrochloride. N-Desethyl Oxybutynin is the the active metabolite Oxybutynin. Oxybutynin is an anticholinergic agent that inhibits voltage-dependent K+ channels[1].

HY-B1470S

Azaperone-d4
Azaperone-d₄ is the deuterium labeled Azaperone. Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

HY-B0520AS1

Benztropine-d3 mesylate

Benztropine-d₃ (mesylate) is the deuterium labeled Benztropine mesylate[1]. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[2][3].

HY-B0520AS

Benztropine-13C,d3 mesylate

Benztropine- ¹³C,d₃ (mesylate) is the ¹³C- and deuterium labeled Benztropine (mesylate). Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[1][2].

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